Abstract

The absolute stereochemistry of the 2-hydroxyglutaric acid present in methanopterin and its α-glutamyl derivative, sarcinapterin, has been determined to be (S). Thus, the absolute stereochemistry of the 2-hydroxyglutaric acid present in the side chain of these modified folates is the same as the L-glutamic acid present in the side chain of folates. Chirality 9:678–680, 1997. © 1997 Wiley-Liss, Inc.

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