Absence of natural group anti-A, anti-B antibodies (isohemagglutinins) and blood transfusion tactics in this blood group

Abstract

Aim. To analyze the clinical data obtained at donor and recipient blood testing obtained in clinical diagnostic laboratory. Methods. Blood of donors and recipients for erythrocyte-containing blood-derived products was examined. Gel method was used for immunologic and hematologic testing. Results. A donor and recipients with the absence of natural group antibodies (isohemagglutinins) were identified. Those subjects were consulted for treatment with blood transfusion. According to the regulations, blood transfusion is provided considering the blood group of recipient. In described cases, serum analysis revealed no natural group antibodies, hence, no antibodies should be present in administered plasma coagulation hemostasis correctors. Conclusion. In the presented clinical cases, due to the absence of natural group antibodies (isohemagglutinins) АВ0 (IV) group serum is preferable if the blood transfusion is needed. Keywords: blood components, natural group antibodies, isohemagglutinins, agammaglobulinemia, Wiskott-Aldrich syndrome, non-Hodgkin’s lymphoma.