Abstract
Commentary on: c-kit1 cells minimally contribute cardiomyocytes to the heart. van Berlo et al. Nature . 2014. doi:10.1038/nature13309 A recent paper by Jeffrey Molkentin9s group using mice with Cre/lox knock-in in the c-kit locus concludes that, contrary to other reports, c-kit+ cells minimally contribute cardiomyocytes to the heart. We believe the authors9 interpretation of the results is problematic because critical data to support their conclusions have not been provided.
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