Abstract

Eosinophilic colitis (EC) is caused by the significant accumulation of eosinophilic polynuclear infiltrate in the colonic mucosa. It is a pathology in infants and children under 2 years of age, but is rarer and less studied in adults. The positive diagnosis is based on clinical, endoscopic, histological and biological arguments. Treatment involves the antigen avoidance diet against the responsible antigen and medical treatment. The clinical symptomatology for adults with eosinophilic colitis is variable and nonspecific. Diarrhea and abdominal pain are the most common signs. There is no histological consensus for the diagnosis. The presence of more than 40 eosinophils per field in at least two different colonic segments could be suggested as a diagnostic criterion. Also, there is no consensus on the treatment of eosinophilic colitis, but the potential efficacy of corticosteroids and budesonide has been demonstrated in the vast majority of cases studied.

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