Abstract
BackgroundAboriginal people living in Canada have a high prevalence of obesity, type 2 diabetes, and cardiovascular disease (CVD). To better understand the pre and postnatal influences on the development of adiposity and related cardio-metabolic factors in adult Aboriginal people, we will recruit and follow prospectively Aboriginal pregnant mothers and their children – the Aboriginal Birth Cohort (ABC) study.Methods/designWe aim to recruit 300 Aboriginal pregnant mothers and their newborns from the Six Nations Reserve, and follow them prospectively to age 3 years. Key details of environment and health including maternal nutrition, glucose tolerance, physical activity, and weight gain will be collected. At birth, cord blood and placenta samples will be collected, as well as newborn anthropometric measurements. Mothers and offspring will be followed annually with serial measurements of diet and physical activity, growth trajectory, and adiposity.DiscussionThere is an urgent need to understand maternal and child factors that underlie the early development of adiposity and type 2 diabetes in Aboriginal people. The information generated from this cohort will assist the Six Nations community in developing interventions to prevent early adiposity in Aboriginal children.
Highlights
Aboriginal people living in Canada have a high prevalence of obesity, type 2 diabetes, and cardiovascular disease (CVD)
There is an urgent need to understand maternal and child factors that underlie the early development of adiposity and type 2 diabetes in Aboriginal people
The information generated from this cohort will assist the Six Nations community in developing interventions to prevent early adiposity in Aboriginal children
Summary
There is an urgent need to understand maternal and child factors that underlie the early development of adiposity and type 2 diabetes in Aboriginal people. The information generated from this cohort will increase our understanding of the contribution of pre and post natal factors to childhood overweight/obesity and type 2 diabetes, and assist the Six Nations community in developing interventions to prevent early adiposity in Aboriginal children. We anticipate this study will be expanded to include other Aboriginal communities across Canada. Competing interests The authors declare that they have no competing interests. Authors’ contributions GW, JW, RM, RA, SM, KKM, KKT, SSA made substantial contributions to conception and design of the study and participated in the writing of the manuscript. All authors read and approved the final manuscript
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