Abstract
Purpose In early childhood, heart transplantation (Tx) can safely be performed using organs from an ABO incompatible (ABOi) donor. This approach broadens the accessible donor pool for the recipient and should impact wait list mortality and waiting time, as shown in single center settings. We sought to identify clinical characteristics of ABOi listed patients (Pt) and impact of ABOi listing on waiting list parameters. Methods The large multi-center registry of the Pediatric Heart Transplant Society captured intention to accept an ABOi donor at listing since 2010. We compared children Results 1083 patients were listed ABOi and 819 ABOc. ABOi-listed patients had significantly lower age and BSA (p Conclusion In the current era patients primarily listed for ABOi still show a higher risk profile compared to ABOc listed patients. Independently, post-Tx survival is equal and wait times are reduced, especially for BG O children. A switch in listing from ABOc to ABOi is associated with worse post-Tx survival probably due to clinical deterioration of the patients while waiting.
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