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Abstract
Coronavirus disease (COVID-19) or (SARS-CoV-2) is a pandemic disease represents a public health crisis that causes actual morbidity and mortality. The disease characterized by respiratory infection and spread worldwide after an outbreak initiated in Wuhan, China, in December 2019. The novel coronavirus disease has been spreading around the world rapidly and declared as a pandemic by WHO. Our aim in this meta-analysis of many different studies to find out the susceptibility of infection by COVID-19 and individuals having specific ABO blood group. This systematic review and meta-analysis covered most of the comparison of many studies carried out since Marsh 2019 up to May 2021, and indicated that blood group A and B was associated with an increased risk of infection (susceptibility) or death (severity), whereas blood group O appears to be protective and associated with a decreased risk of infection or death. Keywords: COVID-19, SARS-CoV-2, ABO blood group, disease susceptibility
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