Abstract
Objective: To identify the abnormalities of lipid profile early in overweight and obese children. Study design: Observational study. Setting: Vydehi Institute of Medical Sciences & Research Centre, Bangalore. Participants: 100 children who are overweight and obese. Outcome Measures: Abnormal lipid profile. Methods: In all patients who are overweight and obese as per IAP growth charts and who are above 6 years of age, a detailed history including antenatal history, birth weight, diet history, personal history were taken. In these patients demographic measures like age, sex, anthropometric measurements weight, height, BMI, waist circumference, waist hip ratio and blood pressure were recorded. In all the patients fasting blood glucose, triglyceride and HDL-C were done. Results: Out of 100 children studied, 61% (61cases) were overweight and 39% (39 cases) were obese. Males were 52% (52 cases) and females were 48% (48 cases). 92 cases had normal birth weight, 6 cases were SGA and 2cases were LGA babies. 85% had TGL levels less than 150 mg/dl and 15% had high or equal to 150mg/dl. 69% of the cases had HDL-C less than 40mg/dl and 31 % of the cases had HDL-C more than or equal to 40mg/dl. Conclusions: By doing lipid profile in overweight and obese children, we can identify abnormal lipid profile in these children early and initiate non pharmacological management, behavioral therapy and if required pharmacological therapy thereby preventing these children from developing metabolic syndrome and its associated long term complications.
Highlights
Childhood obesity appears with a powerful array of cardiovascular risk factors including combined dyslipidaemia, insulin resistance and hypertension and has been shown to be associated with pathologic evidence of accelerated atherosclerosis in autopsy studies.The dyslipidaemia pattern associated with childhood obesity consists of a combination of elevated triglycerides (TG), decreased high density lipoprotein cholesterol (HDL-C), and top normal to mildly elevated low density lipoprotein cholesterol (LDL-C)
Along with overweight or obesity, if there are abnormalities of lipids such elevated TG, decreased HDL C, impaired glucose and hypertension, we call this as Metabolic Syndrome which has long term implications on the child as it grows older
A developing country is already known as Diabetic Capital, has a large number of children with overweight and obesity which further add to the problem [2]
Summary
Childhood obesity appears with a powerful array of cardiovascular risk factors including combined dyslipidaemia, insulin resistance and hypertension and has been shown to be associated with pathologic evidence of accelerated atherosclerosis in autopsy studies. The dyslipidaemia pattern associated with childhood obesity consists of a combination of elevated triglycerides (TG), decreased high density lipoprotein cholesterol (HDL-C), and top normal to mildly elevated low density lipoprotein cholesterol (LDL-C). Along with overweight or obesity, if there are abnormalities of lipids such elevated TG, decreased HDL C, impaired glucose and hypertension, we call this as Metabolic Syndrome which has long term implications on the child as it grows older. This study was done to detect the Pediatric Review: International Journal of Pediatric Research Available online at: www.pediatricreview.in 580 | P a g e abnormalities of lipid profile early in overweight and obese Indian childrenabove 6 years of age
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
