Abnormalities of Glucose and Insulin Metabolism in Exogenous Obesity.

Abstract

s1 May 1965Abnormalities of Glucose and Insulin Metabolism in Exogenous Obesity.Karl E. Sussman, M.D.Karl E. Sussman, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-62-5-1074_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOral glucose tolerance was evaluated in 12 patients with exogenous obesity and in 20 normal subjects. Obese patients were studied on three dietary programs—after diets containing 300 g or 180 g carbohydrate and after total caloric fasting lasting from 5 to 14 days. In obese patients above age 20 years, glucose tolerance was abnormal. Obese patients below 20 years demonstrate minimal impairment of carbohydrate tolerance, which is not statistically significant from normal tolerance tests. The mean plasma insulin level in obese patients before the tolerance tests was 29.5 µU/ml, reaching a maximum of 247.0 µU/ml 120 minutes after glucose administration,... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Denver, Colorado PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1965Volume 62, Issue 5Page: 1074-1074KeywordsBlood plasmaCarbohydratesDietGlucoseGlucose metabolismGlucose toleranceInsulinObesityOral glucose tolerance testOverweight Issue Published: 1 May 1965 PDF downloadLoading ...