Abstract

Objective: Obstetricians, Neonatologists, and Pathologists have studied gross histological analysis of human placentas in search of specific alterations in placental functions that can be correlated with neonatal outcomes. Our study assessed the prevalence of abnormal placental findings associated with non-reassuring fetal monitoring in labor requiring emergent instrumental or cesarean delivery, followed by an excellent neonatal outcome. Study Design: One hundred consecutive emergency deliveries, instrumental or cesarean, performed due to non-reassuring fetal monitoring while in labor were retrospectively evaluated. All patients were low-risk for obstetric complications, and had a singleton, term pregnancy. They had a normal antenatal routine testing and a normal anatomy ultrasound scan at 20 to 22 weeks gestation. Results: There were 35 placentas (35%) with gross placental anomalies at the delivery triage. Additionally 7 placentas (7%) were reported to be abnormal at the pathology examination. Conclusion: The prevalence of abnormal placental findings in our studied population was 42%.

Highlights

  • Obstetricians, Neonatologists, and Pathologists have studied gross histological analysis of human placentas in search of specific alterations in placental functions that can be correlated with neonatal outcomes

  • Our study assessed the prevalence of abnormal placental findings associated with non-reassuring fetal monitoring in labor requiring emergent instrumental or cesarean delivery, followed by an excellent neonatal outcome

  • Obstetricians, Neonatologists, and Pathologists have studied gross and histological analysis of human placentas in search of specific alterations in placental function that can be correlated with neonatal outcomes

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Summary

Introduction

Obstetricians, Neonatologists, and Pathologists have studied gross and histological analysis of human placentas in search of specific alterations in placental function that can be correlated with neonatal outcomes. Further attention to placental analysis including more rigorous guidelines for pathologic diagnosis is needed to delineate which abnormal findings are associated with adverse neonatal outcomes. Per The College of American Pathologists (CAP) guidelines, all human placentas should be inspected and triaged at the delivery room and the abnormal ones should be sent to pathology for a complete examination using specific examination criteria as established by the CAP. As previously determined by Ventolini et al, in a cohort of 88 uneventful deliveries, 42% of placentas had abnormal findings during pathological evaluation. Thirteen of the abnormal placentas (35.1%) showed pathology unassociated with fetal compromise. The purpose of our study was to assess the prevalence of abnormal placental findings associated with non-reassuring fetal monitoring in labor requiring emergent instrumental or cesarean delivery, followed by an excellent neonatal outcome

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