Abstract
BackgroundOsteochondroma is the most common benign bone tumor. However, there are infrequent studies karyotyping solitary osteochondromas. MethodsRetrospective review of the University of California, Los Angeles pathology database was performed for karyotype analyses (N = 522 specimens). ResultsTwo previously undescribed karyotypes were identified. First, was a karyotype showing paracentric inversion of chromosome 7. Second, was a karyotype showing monosomy 3, 6 and 13. ConclusionsAbnormal karyotypes may be more frequently encountered in osteochondroma than previously understood. However, the clinical significance of these abnormalities are yet unknown.
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