Abstract
Summaries for Patients5 December 2000Abnormal Heart Rhythm in Patients with Leukemia Treated with Arsenic TrioxideSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-11-200012050-00007 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Acute promyelocytic leukemia (APL) is a cancer of the blood. Arsenic trioxide is effective in treating cases of APL that have not responded to other therapies. Abnormal heart rhythms are common in patients with arsenic poisoning, so there is concern that dangerous side effects might occur when arsenic is used to treat APL. A previous report found that heart rhythm abnormalities occurred in only 8 of 47 patients with leukemia receiving arsenic; none of these heart rhythms was life-threatening. However, another report described a patient with APL who ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Prolongation of the QT Interval and Ventricular Tachycardia in Patients Treated with Arsenic Trioxide for Acute Promyelocytic Leukemia.” It is in the 5 December 2000 issue of Annals of Internal Medicine (volume 133, pages 881-885). The authors are K Ohnishi, H Yoshida, K Shigeno, S Nakamura, S Fujisawa, K Naito, K Shinjo, Y Fujita, H Matsui, A Takeshita, S Sugiyama, H Satoh, H Terada, and R Ohno.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoProlongation of the QT Interval and Ventricular Tachycardia in Patients Treated with Arsenic Trioxide for Acute Promyelocytic Leukemia Kazunori Ohnishi , Hitoshi Yoshida , Kazuyuki Shigeno , Satoki Nakamura , Shinya Fujisawa , Kensuke Naito , Kaori Shinjo , Yota Fujita , Hirotaka Matsui , Akihiro Takeshita , Shiho Sugiyama , Hiroshi Satoh , Hajime Terada , and Ryuzo Ohno Metrics 5 December 2000Volume 133, Issue 11Page: I-59KeywordsArsenicBloodCancer treatmentDrugsElectrocardiographyHeartLongitudinal studiesPacemakersVeinsVentricular tachycardia ePublished: 5 December 2000 Issue Published: 5 December 2000 CopyrightCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
