Abstract
In two apparently healthy subjects EMG findings have been made of a type not previously encountered. The jitter between the muscle fiber action potentials from two different muscle fibers belonging to the same motor unit was only 2–3 μsec (S.D.), which is far less than that normally obtained (10–30 μsec). The jitter was unaffected by i.v. injection of 15 and 30 μg d-tubocurarine/kg body weight. Normally, a considerable increase of the jitter is seen at these doses. At the dose level 30 μg d-tubocurarine/kg, blocking of occasional discharges was seen, affecting both the fiber potentials simultaneously. Normally either one or the other of the two fiber potentials blocks in any one discharge. A hypothesis is presented whereby an abnormal connection existed between two or more fibers, so that activation of one fiber via its motor end-plate also activated the other fiber.
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