Abstract
Extract: A mathematical model of the Base Excess curve of blood was developed and then programmed into a digital computer coupled to an automatic plotter. Values for serum albumin, globulin and mean corpuscular hemoglobin concentrations were fed to the computer and theoretical Base Excess curves were generated. Normal values gave a curve which closely approximated the experimentally derived curve of SIGGAARD-ANDERSEN. When values characterizing hypoproteinemia, hypochromia or tris-(hydroxymethyl)-aminomethane buffering were introduced, Base Excess curves were produced which varied, often markedly, from the traditional curve. Speculation: Base Excess determinations which employ currently published nomograms or slide rules are subject to significant error when blood is seriously hypoproteinemic, hypochromic, or buffered with tris-(hydroxymethyl)-aminomethane.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
