Abstract
The sinus node is a highly complex biosensor whose function is controlled by extrinsic and intrinsic variables consisting of blood gases and pH, hormonal and nonhormonal chemicals, temperature, stretch, autonomic nervous system, midbrain, and cerebral cortex drive. It is strictly controlled by more than 15 ionic electrical currents. The complexity of these functions explains the difficulty in understanding the physiology, pathology, and treatment of conditions such as inappropriate sinus tachycardia (IST). The Heart Rhythm Society 2015 Expert Consensus Statement defined IST as a sinus heart rate (HR) >100 bpm at rest (mean 24-hour HR >90 bpm not due to primary causes) associated with distressing symptoms of palpitations. Despite IST being a benign condition, sometimes it can be highly symptomatic and debilitating. 1 Sheldon R.S. Grubb B.P. Olshansky B. et al. 2015 Heart Rhythm Society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm. 2015; 12: e41-e63 Abstract Full Text Full Text PDF PubMed Scopus (397) Google Scholar Sinus Node Sparing Hybrid Thoracoscopic Ablation Outcomes in Patients with Inappropriate Sinus Tachycardia (SUSRUTA-IST) RegistryHeart RhythmVol. 19Issue 1PreviewMedical treatment of inappropriate sinus tachycardia (IST) remains suboptimal. Radiofrequency sinus node (RF-SN) ablation has poor success and higher complication rates. Full-Text PDF Open Access
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
