Ability of Pit and Fissure Sealant-containing Amorphous Calcium Phosphate to inhibit Enamel Demineralization.

Feda I Zawaideh,Wasan Kawaja,Arwa I Owais

doi:10.5005/jp-journals-10005-1325

Feda I Zawaideh, Wasan Kawaja + Show 1 more

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https://doi.org/10.5005/jp-journals-10005-1325

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Abstract

ABSTRACTAim: To evaluate the effect of amorphous calcium phosphate (ACP)-containing pit and fissure sealant on inhibition of enamel demineralization in vitro.Materials and methods: Enamel specimens (n = 75) were prepared using freshly extracted noncarious human third molars. Box-shaped cavities (8 × 2 × 2 mm) on the buccal or lingual surfaces were prepared and restored with resin-based sealant (Concise™), ACP-containing sealant (Aegis®) or fluoride-containing sealant (Conseal-F™). The samples were acid challenged in a demineralizing solution of 50 mmol/l lactic acid at pH 5.0 for 4 days. The change in enamel microhardness (ASuH) was calculated. Data were analyzed using one-way analysis of variance (ANOVA) and Tukey’s post hoc test.Results: The mean SuH0 (±SD) (in Vicker’s unit) prior to the acid challenge was: Concise™ (318.83 ± 33.86), Aegis® (331.03 ± 21.52), Conseal-F™ (310.12 ± 34.31). Following the acid challenge, the values dropped in all groups and ASuH (±SD) values were 269.17 ± 47.49, 151.39 ± 23.96 and 175.79 ± 32.39 respectively.Conclusion: The ACP-containing pit and fissure sealant has the potential to inhibit enamel demineralization.How to cite this article: Zawaideh FI, Owais AI, Kawaja W. Ability of pit and fissure sealant-containing amorphous calcium phosphate to inhibit enamel demineralization. Int J Clin Pediatr Dent 2016;9(1):10-14.

Highlights

IntroductionAmorphous calcium phosphate has both preventive and restorative material properties that justify its use in dental cements, sealants, composites and orthodontic adhesives.[1,4] Amorphous calcium phosphate-filled composite resins have been shown to repair 71% of the lost mineral content of decalcified teeth.[1]
Amorphous calcium phosphate (ACP) is a precursor to the formation of hydroxyapatite (HAP), which is the final, stable product in the precipitation of the calcium1-3Department of Preventive Dentistry, Jordan University of Science and Technology, Irbid, JordanAmorphous calcium phosphate has both preventive and restorative material properties that justify its use in dental cements, sealants, composites and orthodontic adhesives.[1,4] Amorphous calcium phosphate-filled composite resins have been shown to repair 71% of the lost mineral content of decalcified teeth.[1]A new pit and fissure sealant containing ACP (Aegis® pit and fissure sealant) has been marketed for use as a light-cured sealant with similar properties to previously used resins
Alsaffar et al[6] demonstrated that Aegis® may provide some protective effect on demineralization of adjacent enamel measuring the amount of mineral loss

Summary

Introduction

Amorphous calcium phosphate has both preventive and restorative material properties that justify its use in dental cements, sealants, composites and orthodontic adhesives.[1,4] Amorphous calcium phosphate-filled composite resins have been shown to repair 71% of the lost mineral content of decalcified teeth.[1]. A new pit and fissure sealant containing ACP (Aegis® pit and fissure sealant) has been marketed for use as a light-cured sealant with similar properties to previously used resins. These materials are encouraging the formation of HAP, which can be used by the tooth for remineralization.

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