Abdominal obesity and ten-year prognosis of patients with myocardial infarction

Abstract

Aim. To assess the relationship of abdominal obesity with left ventricular systolic function and to predict outcomes in patients with MI within 10 years.Methods. 581 medical records of patients enrolled in the Acute coronary Syndrome Registry between 2008 and 2010 were retrospectively reviewed for the period of 10 years. The following clinical endpoints were collected: all-cause mortality, cardiovascular mortality, recurrent myocardial infarction, stroke, hospitalization due to unstable angina and decompensated heart failure. Baseline left ventricular ejection fraction (LVEF) and the presence of abdominal obesity measured as waist-to-hip ratio were collected in all patients.Results. Abdominal obesity was found in 392 (67.4%) patients admitted with MI. The presence of abdominal obesity did not affect main outcomes within 10 years after the indexed event. Cardiovascular mortality was the lowest among patients with abdominal obesity., an association between abdominal obesity and low cardiovascular mortality was found in patients with intermediate LVEF using the risk stratification data based on the severity of systolic dysfunction at discharge. The highest rate of recurrent hospitalization due to unstable angina was found in patients with abdominal obesity and intermediate LVEF.Conclusion. The prevalence of abdominal obesity in MI patients was high (67%). Abdominal obesity appeared to confer protective effects on the 10-year clinical outcomes in patients with low and intermediate LVEF based on all-cause and cardiovascular mortality. The waist-to-hip ratio were significant in the generation of 10-year allcause and cardiovascular disease mortality prediction models in patients with MI.