Abstract
Although several studies showed the efficacy and safety from this procedure, the comparative assessment of adipose tissue by cryolipolysis has not been studied until now. Therefore we investigated the quantitative change of cross sectional areas of abdominal SAT (subcutaneous adipose tissue) and VAT (visceral adipose tissue) following cryolipolysis. A prospective study for twelve subjects with a single session of cryolipolysis on abdomen was performed. We assessed for their height, weight, and waist circumferences, body contours by photographs, and the cross sectional areas of visceral and subcutaneous adipose tissues were measured at umbilicus level by computerized tomography for 2 months. The cross sectional areas in SAT reduced from 243.3 ± 24.7 to 238.5 ± 40.7 cm2 at 2 months post-treatment. Those of VAT reduced from 141.3 ± 46.4 to 125.1 ± 42.8 cm2 at 2 months post-treatment. Cross sectional areas of VAT, and waist circumferences were significantly reduced by 16.2 cm2, 4.1 cm respectively. Additionally visual improvement without unexpected adverse events was noted. In conclusion a single session cryolipolysis demonstrated to reduce visceral adipose tissue as well as waist circumferences tissue for 2 months. Further controlled study would be needed to evaluate for reduction of visceral adipose tissue by cryolipolysis.
Highlights
A prospective study for twelve subjects with a single session of cryolipolysis on abdomen was performed. We assessed for their height, weight, and waist circumferences, body contours by photographs, and the cross sectional areas of visceral and subcutaneous adipose tissues were measured at umbilicus level by computerized tomography for 2 months
The demographic variables, waist circumferences and the cross sectional areas of adipose tissue described at baseline and 8th week
Their waist circumferences significantly decreased by 4.1 ± 6.3 cm (P = 0.023), both of weight and BMI increased by 0.1 ± 1.2 kg (P = 0.777), 1.9 ± 0.6 kg/m2 (P = 0.528) (Table 1)
Summary
Whereas previous study considers visceral adipose tissue as the major culprit to cardio-metabolic mortalities, surgical fat reduction can handle subcutaneous adipose tissue only [1]. Lee tion or lipectomy which are invasive methods with risks of infection, hemorrhage, scarring [2]. It has some limitation such as expensiveness, and longer postop care, postop mortalities, even without metabolic improvement [3]. Cryolipolysis may be considered as one of replaceable applications to surgical fat reduction approaches for noninvasiveness and selective reduction of subcutaneous adipose tissue without injuries of surrounding tissues since US Food and Drug Administration approved it in 2010 [4] [5]
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