AB1697 COMPARISON OF DISEASE ACTIVITY, INFLAMMATORY BIOMARKER, FUNCTIONALITY, PARTICIPATION AND BIOPSYCHOSOCIAL STATUS OF INDIVIDUALS WITH JIA ACCORDING TO THE PRESENCE OF UPPER EXTREMITY INVOLVEMENT

Abstract

BackgroundMusculoskeletal involvements due to synovitis and tenosynovitis in the upper extremity joints of individuals with JIA negatively affect their daily living activities with the progression of the process [1-2].ObjectivesThe aim of this study is to compare the disease activity, inflammatory biomarker, functionality, participation and biopsychosocial status of individuals with JIA according to the presence of upper extremity involvement.MethodsForty individuals (21 girls, 19 boys) who were followed up with the diagnosis of JIA between March and December 2022 were included in our study. Individuals whose demographic information was obtained were divided into two groups as those with isolated upper extremity involvement (JIAUE+, n=11) and those without active and/or sequela joint involvement in the upper or lower extremities (JIAULE-, n=29). Disease activity (JADAS-71 and BASDAI), inflammatory biomarker (ESR and CRP), functionality (Childhood Health Assessment Questionaire (CHAQ)) [3], participation (The Child and Adolescent Scale of Participation (CASP)) [4] and biopsychosocial status (Juvenile Arthritis Biopsychosocial and Clinical Questionnaire (JAB-Q)) [5] was evaluated.ResultsWhile there was no difference between the two groups in terms of age, gender and BMI(p>0.05), in the JIAUE+ group, JADAS-71 (p=0.012), CRP (p=0.041), CHAQ-Pain (p=0.048), CHAQ-Overall Impact (p=0.003), JAB-Q Child Form functionality (p=0.033) and total score (p=0.009) were found to be significantly higher than the JIAULE- group. All sub-parameters (home (p=0.009), community (p<0.001), school (p=0.005), home and community living activities (p=0.044)) and total score of CASP (p=0.003) were found to be significantly lower in the JIAUE+ group.ConclusionDisease activity and inflammatory biomarker levels of JIAUE+ individuals were higher than JIAULE- individuals. In addition, pain, functionality, participation and biopsychosocial status of JIAUE+ individuals were worse than JIAULE- individuals. Our results were consistent with the literature, which revealed that functionality, school performance, and general quality of life were negatively affected in JIAUE+ individuals [6]. The data obtained from the study revealed that the upper extremity joint involvement of individuals with JIA showed more negative effects than those without involvement. With these results, the need for a rheumatologist-physiotherapist-occupational therapist interdisciplinary team understanding was emphasized in order to include individuals with JIA with upper extremity involvement in the exercise-physical activity and participation processes in daily life at the earliest stage, taking into account the disease activity.