AB1536 HOME SPIROMETRY AND OXIMETRY MONITORING IN PATIENTS WITH CONNECTIVE TISSUE DISEASE RELATED INTERSTITIAL LUNG DISEASE – A SINGLE CENTRE PROSPECTIVE STUDY

Abstract

BackgroundInterstitial lung disease (ILD) is an important complication in patients with connective tissue disease causing significant impact on quality of life with a high mortality rate.ObjectivesWe aim to determine the feasibility of home spirometry and oximetry reading, focusing on patients with connective tissue disease related ILD.MethodsPatients with connective tissue disease related interstitial lung disease (CTD-ILD), idiopathic pulmonary fibrosis (IPF) and familial pulmonary fibrosis (FPF) were recruited and followed prospectively for 12 months. A handheld spirometer (MIR Spirobank Smart) and oximeter linked to a real-time electronic health journal via a smartphone app to record daily spirometry and oximetry readings were provided. Patients were asked to perform one or more spirometry manoeuvres at approximately the same time daily to reduce variability, with the best value for each day used for analysis.Results62 patients with CTD-ILD, 31 IPF and 21 FPF were recruited. The median age was 66, 71 and 69 years respectively. 47.8% were males. Preliminary data on 99 patients demonstrated median forced vital capacity (FVC) predicted were 82.5% in the CTD-ILD, 84.1% in IPF and 83.7% in FPF cohorts with median follow-up of 208 days. The median oxygen saturation (SpO2) for 9501 readings was 96% in all three cohorts. 27.8% experienced Raynaud’s phenomenon but only 5.6% in the CTD-ILD required an ear oximeter due to inaccurate measurement of oxygen saturation secondary to Raynaud’s phenomenon.Table 1.Forced Vital Capacity (FVC) and SpO2 readings in patients with CTD-ILD, IPF and FPFCTD-ILDIPFFPFNo. of Patients542817Median Age (years)667169No. of FVC Readings515733841624Median FVC (L)2.352.662.06Median FVC Predicted (%)82.584.183.7No. of SpO2 Readings447533501676Median SpO2 (%)969696ConclusionHome monitoring of FVC and oximetry in patients with CTD-ILD are feasible, empowers patients and generates granular data which can be useful in the detection of rapidly progressing ILD allowing early management.REFERENCES:NIL.Acknowledgements:NIL.Disclosure of InterestsNone Declared.