Abstract
Background: Desmoid tumors are benign fibromatous tumours arising from dysregulated myofibroblast proliferation 1 within musculoaponeurotic structures. Classically, these tumours do not metastasise but can cause significant morbidity and mortality due to their infiltrative pattern and/or local invasion. Historically, surgical resection with the aim of achieving histologically negative margins has been the cornerstone of therapy, however in recent years a shift towards an observational or pharmacological approach is advocated. A paucity of data regarding outcomes remains, with no consensus as to the most effective therapeutic approach. Therefore, we aimed to assess the current evidence base for the surgical management of abdominal desmoid tumours in terms of success, recurrence and morbidity.
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