Abstract

Background: Surgical treatment of patients with rheumatoid arthritis (RA) is associated with an increased risk of complications. It can be caused by: an inflammatory process, the osteoporosis, the reduced physical activity, the severity of functional impairment, long-term glucocorticoid therapy, biologic and disease-modifying antirheumatic drugs. All of the above reasons provide elongated wound healing period, the development of infectious complications, increased risk of periprosthetic fractures. Objectives: to provide a comparative analysis of local complications of hip and knee arthroplasty in RA and osteoarthritis (OA) patients. Methods: We analyzed 2142 operations: hip (n = 1177) and knee (n = 965) replacement, which were performed to patients with RA and OA between 1998 and 2018. Results: There were 2142 hip and knee arthroplasty performed, including 1118 operations on patients with RA and 1024 operations on patients with OA. The number of local complications after total hip replacement was 155 (7.24%): 96 (8.59%) of them were patients with RA and 59 (5.76%) patients with OA. There were 1177 hip arthroplasty performed, including 467 operations on patients with RA and 710 operations on patients with OA. The number of local complications after total hip replacement was 85 (7.22%): 48 (10.28%) of them were patients with RA and 37 (5.21%) patients with OA. There were 965 knee arthroplasty performed, including 651 operations with RA patients and 314 operations in patients with OA were performed. The number of local complications after total knee replacement was 70 (7,25%): 48 (7.37%) of them were patients with RA and 22 (7.00%) patients with OA. We revealed a significantly greater number of complications in patients with RA (p Conclusion: Local complications after hip and knee arthroplasty with RA patients (8.59%) more than in OA patients (5.76%) in 1.5 times. It shows us that the operative treatment of patients with RA requires a special approach and more gentle management of patients with RA in co-operation with rheumatologist and careful treatment of the bone with surrounding tissues during the surgery. Disclosure of Interests: None declared

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