AB1090 IMPACT OF THE COVID19 PANDEMIC ON THE SOCIAL BEHAVIOR OF PATIENTS WITH RHEUMATIC DISEASES

Abstract

BackgroundDepression in rheumatic diseases negatively influences the support network and the perception of company of these patients (1).ObjectivesTo describe how the COVID-19 pandemic affects the social activitiesn patients with chronic rheumatic diseases such as Rheumatoid arthritis (RA), Systemic Lupus Erithematosus (SLE) and Spondyloarthritis (SpA).MethodsDesign: Observational, longitudinal study of a series of patients. Patients: RA (ACR/EULAR 2010 classification), SpA (ASAS/EULAR 2010 criteria), and SLE (ACR 1997 criteria) patients, age ≥ 18 years. Questionaries for the evaluation of participation in social activities is the Patient Reported Outcomes Measurement Information Systems (PROMIS) v2.0 Short-Form (8 items, PROMIS-APS) at baseline (OCT to DEC 2019) and after 18 months of pandemic (SEP to DEC 2021) were performed. Variables evaluated were: social activities in terms of various factors, such as satisfaction with social roles mobility, depression, companiony social isolation, emotional support, instrumental support, support via information and ability to participate in social activities. All the variables were evaluated using the PROMIS questionnaire with quantitative scores. We also recorded demographic, clinical, and comorbidity data. Statistical analysis: Multivariate Linear Regression (Dependent variable: PROMIS ability to participate in social activities 18 months COVID19) was performed.ResultsWe recruited 91 patients, 31 (34.1%) RA, 30 (33%) SpA y 30 (33%) SLE. The 3 groups were well balanced in terms of clinical-epidemiological characteristics, except that patients with SLE were younger (mean 45 years) than patients with RA (53 years) and SpA (55 years) (p = 0.004) and because most of the patients with RA and SLE were women (97%) compared to those with SpA (60%) (p <0.001).There was a worsening after 18 months of the COVID19 pandemic in the mean scores of the PROMIS for: satisfaction of the social role (26.9 ± 8.7 vs 25.3 ± 8.4; 0.046), depression (14.7 ± 7, 6 vs 16.1 ± 8.4; p = 0.044) and for the ability to participate in social activities (27.7 ± 7.2 vs 26.1 ± 6.8; p = 0.020). By diagnoses, the ability to participate in social activities was very similarbetween the different groups except for worse mobility in patients with RA and SpA compared to SLE, both at baseline and at 18 months of the pandemic. SLE patients worsened more after 18 months of the COVID19 pandemic in social role satisfaction, depression, instrumental support and ability to participate in social activities.In the multivariate analysis, the ability to participate in social activities at 18 months of the COVID19 pandemic was inversely associated with the diagnosis of SLE compared to the rest (ß [95% CI], -2.60 [-4.62 - 0.58]; p = 0.012) and depression (ß [95% CI], -0.23 [-0.39, -0.08]; p = 0.004); and directly with social role satisfaction (ß [95% CI], 0.18 [0.10-0.35]; p = 0.031), mobility (ß [95% CI], 0.13 [0.07-0.20]; p = 0.001) and company (ß [95% CI], 0.32 [0.11-0.60]; p = 0.023).ConclusionAt baseline evaluation, social activities were affected by the impact of rheumatic disease. After 18 months of the pandemic-COVID19, patients with RA and SPA remain stable but SLE patients significantly worsened their social role and depression.