AB1067 ASYMPTOMATIC HYPERURICEMIA AND ASSOCIATED FACTORS IN MALE PATIENTS VISITED HANOI MEDICAL UNIVERSITY HOSPITAL

Abstract

BackgroundAsymptomatic hyperuricemia prevalence in Vietnamese men has rose over the past several years. This leads to gout and increase cardiovascular risk.ObjectivesTo assess the prevalence of asymptomatic hyperuricemia and associated factors in male patients who had medical check-ups in Hanoi Medical University Hospital.MethodsAll asymptomatic hyperuricemia male patients over 18 years old, had medical check-ups in outpatient clinics from January 2020 to May 2021. Exclude criteria included patients having medicine which affected serum uric acid (allopurinol, probenecid, sulfinpyrazone, salicylate, phenylbutazone, ascorbic acid, ethambutol, pyrazinamide, ect.), had acute diseases, diabetes type 1, chronic kidney disease and malignancies. All patients were tested for serum uric acid, total Cholesterol, Triglyceride, HDL-C, LDL-C and fasting serum glucose using Roche Cobas 6000 analyzer. Age, body mass index, alcohol consuming, physical activities and comorbidities were identified.Results798 male patients over 18 years old were included in the study. Mean age was 39.5 ± 11.2, overweight and obesity rate was 31.5% and 29.8%, respectively. 41.4% patients had hyperuricemia with mean serum uric acid was 405.2 ± 81.2 μmol/l (highest was 820 μmol/l). We found that the factors associated to hyperuricemia in men were: the presence of hypertension (OR 1.64, 95% CI 1.1 -2.34), dyslipidemia (OR 2.37, 95% CI 1.73-3.24) and alcohol consuming (OR 2.16, 95% Cl 1.6-2.8). We did not find association between smoking, physical activities, impaired glucose tolerance with hyperuricemia.ConclusionAlcohol consuming, dyslipidemia and hypertension were associated with higher risk of incident asymptomatic hyperuricemia in Vietnamese men.Disclosure of InterestsNone declared