Abstract
Background: Haemoglobin (Hb) electrophoresis is used as a screening tool to identify thalassemias and haemoglobinopathies. It allows for the quantification of HbA, HbA2, HbF and other Hb variants. An accurate diagnosis and identification of different hemoglobin variants is important for epidemiological studies and management and prevention of the major haemoglobin disorders. We aimed to evaluate the performance of Sebia capillarys 2, using capillary zone electrophoresis (CE), and the BioRad Variant II, using high pressure liquid chromatography (HPLC) in detection of Hb variants.
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