AB0870 IS THE INCIDENCE OF GOUT SIMILAR TO OTHER RISK FACTORS IN PATIENTS PRESENTING WITH STROKE OR MYOCARDIAL INFARCTION?

Abstract

Background Gout is a common form of inflammatory arthritis. The prevalence of gout in Europe is between 0.9-2.5% with rates as high as 4% reported in Ireland.1 Studies have suggested gout as a risk factor in patients presenting with myocardial infarction (MI) and stroke (CVA).However the incidence gout in patients presenting to hospital with MI or CVA in Ireland has not previously been assessed. Objectives The aim of this study was to assess the incidence of gout in patients presenting with CVA and MI in Ireland. A further objective was to explore if the incidence of gout is similar to other risk factors such as hypertension, diabetes mellitus and dyslipidemia in Irish patients presenting with CVA and MI. Methods The Hospital In-Patient Enquiry Scheme ( HIPE) was used to identify patients admitted with stroke or myocardial infarction from 62 acute public hospitals in Ireland from January 2007 until December 2017. HIPE is a national database which records coded hospital admission and demographic, clinical and administrative data on discharges from, and deaths in, acute public hospitals nationally.2 Discharges are coded using the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification (ICD-10-AM), Australian Classification of Health interventions (ACHI), Australian Coding Standards (ACS), 8th Edition. Age, gender and number of patient admissions with MI or CVA with gout, diabetes, hypertension, peripheral vascular disease(PVD) and hyperlipidemia were recorded. Results From 2007 until 2017, 64,867 were admitted with a diagnosis of CVA in Ireland. The age and gender of patients admitted with a principal diagnosis of CVA are outlined in Table 1. 70,628 patients were admitted with MI. In the CVA population,14.5% of patients had diabetes. Incidence of gout in patients with CVA(0.7%) was similar to patient with the risk factors of hyperlipidemia (0.91%) and PVD (0.94%). The incidence of gout in the MI group (0.5%) was lower when compared to the stroke group (0.77%). The presence of diabetes as a risk factor ( 6.7%)was significantly higher compared to gout (0.5%)in patients admitted with myocardial infarction. Chart one outlines the incidence of each risk factor in patients discharge with a primary diagnosis of MI in Ireland between 2007 and 2017 Conclusion The incidence of gout in patients presenting with CVA or MI in Ireland was low compared to other risk factors including diabetes. In patients presenting with MI then incidence of gout is lower than in patients presenting with CVA.