AB0714 COMPARISON OF THE EFFECT OF SUBACROMIAL ADMINISTRATION OF HYALURONIC ACID AND PLATELET RICH PLASMA IN CASES OF DAMAGE TO THE TENDONS OF THE ROTATORS OF THE SHOULDER IN INDIVIDUALS OF DIFFERENT AGE GROUPS

Abstract

Background:Everyone has had shoulder pain at least once in their life. From 70 to 80% of chronic pain in the shoulder joint is associated with subacromial impingement syndrome. The use of non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids does not always meet the needs of patients and have a number of adverse reactions. Local administration of PRP and HA preparations is widely used for chronic shoulder pain. However, the question of the effectiveness of these drugs in patients of different ages has been insufficiently studied.Objectives:To compare the efficacy of GLA and PRP in patients with chronic shoulder pain by age.Methods:The study group included 100 patients, 46% women and 54% men, aged 51.5 ± 15.1, with chronic shoulder pain (≥3 months) caused by damage to the tendons of the muscles of the shoulder rotators. Patients <45 years old accounted for 34%, patients ≥45 years old - 66%. All patients were randomly divided into 2 groups. Patients in group 1 received 2 consecutive subacromial injections of GLK, groups 2 - 3 consecutive subacromial injections of PRP. Pain dynamics were assessed using a 100-mm visual analogue scale (VAS), functional impairments according to ASS (American Shoulder and Elbow Surgeons Assessment) and CS (Constant Score), and a decrease in the need for NSAID use after 6 months. after the course of treatment.Results:The dynamics of pain and functional disorders in the treatment of GLC and PRP did not differ. The pain decreased from 57.6 ± 17.8 to 30.2 ± 26.3 and 56.0 ± 14.6 to 31.8 ± 26.3 (p = 0.768), ASS from 54.7 ± 15.1 to 77.3 ± 22.5 and 54.8 ± 13.8 to 74.6 ± 22.4 (p = 0.552), CS from 47.8 ± 16.9 to 65.6 ± 19.3 and 59.2 ± 14.4 to 66.9 ± 17.4 (p = 0.245). In general, with the treatment of GLA and PRP, the dynamics of pain and functional disorders was significantly better in patients <45 years old than in patients ≥45 years old. So, pain according to VAS after 6 months. was 22.4 ± 26.3 and 35.5 ± 26.2 (p = 0.022), ASS 83.3 ± 20.9 and 72.1 ± 22.6 (p = 0.017), CS 76.2 ± 16, 1 and 63.2 ± 18.2 (p = 0.001). There was no need to take NSAIDs in 82.4% and 65.2% of patients (p = 0.103). No serious adverse reactions have been reported with the treatment of GLC and PRP.Conclusion:The efficacy of GLA and PRP in chronic shoulder pain caused by damage to the tendons of the muscles of the rotator of the shoulder does not differ. The clinical response to both drugs was significantly higher in those under 45 years of age.Disclosure of Interests:None declared