Abstract

Background: During pancreatectomy for ductal adenocarcinoma (PDAC) an intra-operative frozen section analysis of the transection margin is usually performed to achieve an R0 resection. An extension of the resection is required for positive margins until a total pancreatectomy (TP). However, it is unclear whether an extended resection up to TP leads to a survival advantage. This study aims to evaluate disease-specific (DSS) and disease-free (DFS) survival in patients who underwent TP for PDAC compared to standard or extended pancreaticoduodenectomy (PD).

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