AB0565 Discontinuance of methotrexate and prednisolone in treatment with tocilizumab but not with infliximab or etanercept in rheumatoid arthritis patients with high disease activity. (Monotherapy by tocilizumab)

Abstract

BackgroundIL-6 and TNF-α play critical roles in inflammation of rheumatoid arthritis (RA). Antibodies against these cytokines, biologics, show strong anti-inflammatory effects and have changed the therapy of RA dramatically, but...