Abstract
Background: Acute gastrointestinal bleeding results in significant morbidity, cost and mortality. Tranexamic acid (TXA), an antifibrinolytic drug, has been proposed to reduce mortality, however many studies report conflicting results. The aim of this review was to perform a systematic review and meta-analysis of randomized clinical trials (RCTs) to evaluate the efficacy and safety of TXA for acute gastrointestinal bleeding.
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