Abstract

Background: Lymphoepithelioma-like cholangiocarcinoma (LELCC) is a rare variant of intrahepatic cholangiocarcinoma, which is highly associated with Epstein-Barr virus (EBV) infection and abundant lymphoplasmacytic cells infiltration. However, the genetic background of LELCC and the immune profiling of their microenvironment remain largely un-elucidated.

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