AB0311 The 158vv fcgamma receptor iiia genotype predicts a positive response to rituximab in rheumatoid arthritis: Analysis in a large cohort of italian patients

Martina Fabris ,Maurizio Benucci ,Angelo Semeraro ,Valentina Carraro ,Marcello Govoni ,Viviana Ravagnani ,Marco A Cimmino ,Lorenzo Cavagna ,Alen Zabotti ,R Pellerito ,Elena Pontarini ,Roberto Caporali ,Domenico Biasi ,Mariangela Manfredi ,Marta Saracco ,Laura Bazzicchi ,Luca Quartuccio ,P Morassi,Roberto Bortolotti ,Fabio Fischetti ,Fabiola Atzeni ,Stefano Bombardieri ,Salvatore De Vita

doi:10.1136/annrheumdis-2012-eular.311

AB0311 The 158vv fcgamma receptor iiia genotype predicts a positive response to rituximab in rheumatoid arthritis: Analysis in a large cohort of italian patients

Martina Fabris , Maurizio Benucci + Show 21 more

https://doi.org/10.1136/annrheumdis-2012-eular.311

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Journal: Annals of the Rheumatic Diseases

Publication Date: Jun 1, 2013

Affiliation: University of Udine, Nuovo Ospedale San Giovanni di Dio, University of Padua, University of Ferrara, University of Verona, University of Genoa, Policlinico San Matteo Fondazione, A. O. Ordine Mauriziano di Torino, University of Pisa, Ospedale Santa Chiara, University of Trieste, Luigi Sacco Hospital

#Large Cohort Of Italian Patients #Influencing Disease Course + Show 8 more

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Abstract

BackgroundReceptors for IgG play an important part in immune complex clearance. Several studies have investigated the polymorphism 158V/F of Fc fragment of IgG (FcgR) type IIIa as genetic factor influencing...

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