AB0148 Differential Peripheral B-Cell Phenotype in Patients with Primary Sjögren's Syndrome (PSS) Compared To Secondary Sjögren's Syndrome Associated with Systemic Lupus Erythematosus (SLE/SS)

N.L Thompson,E Jury,D.A Isenberg,C Ciurtin

doi:10.1136/annrheumdis-2016-eular.3965

AB0148 Differential Peripheral B-Cell Phenotype in Patients with Primary Sjögren's Syndrome (PSS) Compared To Secondary Sjögren's Syndrome Associated with Systemic Lupus Erythematosus (SLE/SS)

N.L Thompson, E Jury + Show 2 more

https://doi.org/10.1136/annrheumdis-2016-eular.3965

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Journal: Annals of the Rheumatic Diseases

Publication Date: Jun 1, 2016

Affiliation: University College London

#Systemic Lupus Erythematosus #Primary Sjogren's Syndrome + Show 8 more

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BackgroundPeripheral B-cell abnormalities are a feature of both lupus (SLE) and primary Sjogren's syndrome (pSS). However, whereas patients with pSS have increased frequencies of Bm1/Bm2 (naïve), Bm2' (germinal centre founders)...

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