Abstract
Background: According to the WHO classification, thymic epithelial tumors (TET) are classified from type A thymoma to thymic carcinoma, though for pathological diagnosis a type B3 thymoma can be difficult to distinguish from a thymic carcinoma, which is a rare malignancy and its treatment is challenging. Recent studies have demonstrated that L-type amino acid transporter 1 (LAT1) is a cancer-specific amino acid transporter on the membrane of many different types of cancer cells, while its expression has been associated with poor prognosis in cases of malignancy. The purpose is to investigate the differences in expression of LAT1 among TETs and its impact on prognosis of affected patients.
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