Abstract
Background: Pancreatic cancer (PC) is a highly lethal malignancy of digestive system, and nearly 80 percent of PC patients have lost the chance of surgery due to the lack of early diagnosis. For these patients, the only effective treatment (chemotherapy) is largely limited by drug resistance. Therefore, it is urgent to develop new therapy for PC. Endoscopic ultrasound (EUS) guided Iodine 125 (I125) seeds brachytherapy is a novel way of radiotherapy, and its role in the treatment of advanced malignant tumors is not fully explored. This study is to explore the efficacy of I125 brachytherapy on advanced pancreatic cancer.
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