Abstract
Background: Thymoma and thymic carcinoma are the most common malignancies of the anterior mediastinum. Additionally, thymoma has a unique association with autoimmune disorders, notably myasthenia gravis (MG). Histologic classification of thymic epithelial tumors (TETs) has been largely based on the gross description of the epithelial cell appearance and the relative abundance of associated lymphocytes. A comprehensive molecular analysis of TETs has not heretofore been conducted.
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