Ab. No. 30 The Accuracy of 10 G Monofilament Use for Clinical Screening of Diabetes Peripheral Neuropathy Among Indian Population

Abstract

Introduction: The purpose of this study was to test the diagnostic accuracy of the 10g monofilament to screen for diabetic peripheral neuropathy (DPN) in India. The study further assessed the effect of physical activity, footwear use, and occupation on the outcome. Methods: Non-probabilistic purposive sampling was used to recruit patients with T2DM to assess the diagnostic utility of the 10 g monofilament. A total of 160 participants were recruited and divided into 4 groups. Each group consisted of 40 participants with 20 under each category described as “Physical Worker Vs Non- physical worker” (n= 40), “Barefoot vs. footwear” (n=40), “Use of Slipper at Home Vs No-slippers use at home” (n=40), “Agriculture Vs Non- agriculture” (n=40). 10 g monofilament was used to detect the presence of protective sensation towards screening of DPN against biothesiometer (Vibration Pressure Threshold). Result: The area under the ROC (receiver operating characteristic) curve was 0.6 for identifying DPN using the 10 g monofilament. Physical work (p=0.04), footwear (p=0.04), slipper use at home (p=0.02), and occupation (p=0.02) impacted the diagnostic utility of the 10g monofilament. Conclusion: This study shows that the 10 g monofilament has limited accuracy for detecting DPN in the Indian population and this is further affected by occupation, socioeconomic and religious practice.