A9038 The prevalence of metabolically healthy and unhealthy obesity using different criteria

Abstract

Objectives: To assess the prevalence of metabolically healthy obese (MHO) and metabolically unhealthy obese (MUO) using different definitions. Methods: The data were taken from a nation-wide survey on hypertension in China conducted in 2013–2015. Population-based sample of 4757 adults (male 51.1%) aged 35 years and older in Beijing provided data on BMI and metabolic status. Obesity was defined as BMI ≥28 kg/m2, and definitions of metabolic abnormalities were from 5 sets of metabolic syndrome or cardiometabolic abnormalities including the Adult Treatment Panel III (ATP-III), Karelis, Wildman, Chinese Diabetes Society (CDS) and homeostasis model assessment (HOMA) index. Results: The prevalence of obese was 24.3% (1155/4757). The highest prevalence of MHO (13.6%, 95% CI 11.0–16.2) was obtained from the HOMA criteria, followed by CDS, ATP-III, and Wildman. The lowest were from Karelis criteria (4.2%, 95% CI 1.4–7.0). The prevalence of MUO from the highest to the lowest were ranged on the contrary to MHO, the highest was Karelis (20.1%, 95% CI 17.6–22.6) and the lowest was HOMA (10.6%, 95% CI 7.9–13.3). The prevalence of MHO in criteria of ATP-III, Wildman, CDS and HOMA increased with age and reached the peak at age 45 years, then declined and slightly rose after age 80 except for Wildman criteria. The age-specific prevalence of MUO increased with age before 60–64 years and then declined after age 65 regardless of which criteria used. After age 84, the prevalence defined by the criteria of ATP-III and CDS kept on declining continuously, while an increment was observed in the prevalence defined by Karelis, Wildman and HOMA. Conclusion: The variations in the prevalence of both MHO and MUO were magnitude, and this may due to the heterogeneity of the definitions of metabolic disorder. Large cohort studies are needed in the future.