A6550 Trends in Lipids and Lipoproteins among Adults in Northwestern Xinjiang, China, 1998–2015

Abstract

Objectives: Socioeconomic, educational and health care conditions have improved in Xinjiang. However, updated data is unavailable on the prevalence of dyslipidemia and trends in lipid profiles. Therefore, aim was to explore trends in serum lipids during 1998–2015 and to provide clues for future prevention. Methods: We conducted surveys to adult residents in Hefeng, Fuhai and Fukang area using similar methods during 1998–2015. Data collected in 1998, 2000, 2007, 2008 and in 2015 were divided as 1998, 2007, and 2015 groups. Dyslipidemia was identified based on the prevention standard proposed of dyslipidemia in China in 2016 and related factors were analyzed. Results: A total of 5142 adults (57.3% women) were screened including 1059 in 1998, 2144 in 2007 and 1939 in 2015. Mean TC was the lowest in 2015 (4.59 ± 0.95 mmol/L), compared to 1998 (4.79 ± 1.15 mmol/L) and 2007 (5.17 ± 1.04 mmol/L). Mean LDL-C was the lowest in 2015 (2.67 ± 0.78 mmol/L), compared to 2007 (2.87 ± 1.05 mmol/L), and 1998 (3.53 ± 1.09 mmol/L). Mean TG in 2015 (1.11 ± 0.87 mmol/L) was lower than in 2007 (1.58 ± 1.28 mmol/L). Mean HDL-C in 2007 (1.50 ± 0.50 mmol/L) and in 2015 (1.44 ± 0.33 mmol/L) was higher than in 1998 (1.08 ± 0.36 mmol/L). Compared to 1998, the age-standardized prevalence of dyslipidemia, high TC, low HDL-C and high LDL-C in 2015 reduced by 68.5% (16.9% vs 53.6%), 45.7% (5.0% vs 9.2%), 82.1% (7.2% vs 40.3%), and by 82.1% (4.4% vs 24.6%), whereas that of high TG increased by 121.9% (7.1% vs 3.2%). Obesity (OR = 1.92), elevated fasting glucose (OR = 2.48), smoking (OR = 1.29), and drinking (OR = 1.32) were associated with higher prevalence of dyslipidemia. Conclusion: Favorable trends in lipid metabolism have occurred in Xinjiang over the past 17 years. Controlling weight, smoking and alcohol intake may be at high priority of future health promotion.