A6435 Relationship between anthropometric adiposity indexes and hypertension among Chinese adults aged 35–70 years

Abstract

Objectives: To analysis the association of hypertension risk with body mass index (BMI), waist circumstance (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) based on China part of the Prospective Urban Rural Epidemiology study (PURE-China). Methods: 44,258 participants were recruited between 2005 and 2009 from urban and rural area of 12 administrative regions in China. Hypertension was defined when met one of the following items: taking antihypertensive drugs; history of hypertension diagnosis; SBP ≥ 140 mmHg and or DBP ≥ 90 mmHg. Logistic regression analysis was used to calculate odds ratio (OR) and area under receiver operating characteristic curve (AUC) as well as their respective confidence interval (CI) to evaluate the above-mentioned associations. Results: The highest OR was observed for WHtR in both women (OR 2.15, 95% CI: 2.06–2.25) and in men (OR 2.45, 95% CI: 2.31–2.60) in adjusted models. WHtR had the strongest predication abilities of hypertension risk (AUC 66.5%, 95% CI: 66.0%–67.1%) in unadjusted models, but BMI showed strongest prediction abilities in adjusted models (AUC, 73.7%; 95% CI, 73.2%, 74.2%) among both gender, as well as males (AUC, 71.1%, 95% CI, 70.4%, 71.9%) and females (AUC, 75.6%, 95% CI, 75.0%, 76.2%) (Table 1). Conclusion: WHtR had the strongest associations with hypertension risk, but BMI may not be ignored in the screening of hypertension risk.