A604 Improvement in Hemoglobin A1c after Laparoscopic Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in an Ethnically Diverse Population

Abstract

Abstract Background Obesity is a well-known risk factor for the development of type 2 diabetes mellitus (T2D). The efficacy of bariatric surgery in reducing weight with resulting improvement in T2D has been reliably demonstrated. Objectives We investigated and compared the effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) on hemoglobin A1c (A1C) levels in a predominantly Hispanic and African–American population. Settings Community Hospital in New York, New York, United States Methods This is a retrospective review of a 5-year data from a single center where patients with diabetes who underwent LRYGB or LSG were included. A1C levels and body mass index (BMI) were analyzed preoperatively and then annually postoperatively for up to 5 years. Improvements in A1C were compared between the two groups after adjusting for age, sex, race, and hypertension with linear mixed-effects or logistic regression models. Results Of the 676 included patients, 84.8% were females and the mean age was 47 years. A1C levels decreased significantly (p 0.05): 24% vs. 17% (2 years), 22% vs. 16% (3 years), 22% vs. 13% (4 years), and 17% vs. 10% (5 years). Changes in BMI were not correlated to changes in A1C at various study points. Conclusion Both LRYGB and LSG resulted in significant decreases in A1C levels and are correlated with changes in BMI. LRYGB had the greatest effect at 1-year postoperatively. There was no significant difference in A1C reduction for LRYGB and LSG after 1-year postoperatively in this predominantly Hispanic and African American cohort.