Abstract

The human diet became unnaturally hyper-caloric, poor in fiber, predigested by cooking and refining. and extremely easy to be absorbed in more proximal portions of the bowel, creating peaks of nutrient absorption. The ideal metabolic surgery procedure should provide positive interference with the neuroendocrine control of hunger and satiety not cause harm to important digestive functions unrelated to obesity, like the gastric, pyloric and duodenal functions. The single anastomosis sleeve ileal (SASI) bypass is a Novel Metabolic/Bariatric Surgery operation based on mini gastric bypass operation and Santoro's operation in which a sleeve gastrectomy is followed by a side to side gastro-ileal anastomosis. The purpose of this study is to report the 2 years’ outcomes of SASI bypass as a therapeutic option for obese T2DM patients.

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