A334 - Does Coexistence of Non-alcoholic Fatty Liver Disease and Type-2 Diabetes Impact Weight Loss or Remission of Type 2 Diabetes after Gastric Bypass?

Abstract

Background: Obesity and type-2 diabetes (T2D) are risk factors for non-alcoholic fatty liver disease (NAFLD), and Gastric Bypass (RYGB) is an effective treatment for obesity, T2D and NAFLD. While 78% of patients of white race with obesity and T2D have coexisting NAFLD, individuals of black race have been found to have a significantly lower prevalence of NALFD (34%, p<.01), independent of T2D status. The impact of the presence of NAFLD and race on T2D pathophysiology and remission rates after RYGB is under scrutiny. We investigated the possible effect of NAFLD or race on percentage of excess weight loss (%EWL) and T2D remission after RYGB.