A2.08 Extrathymic autoimmune regulator (AIRE) expression can be induced in dendritic cells by CD40-mediated activation of noncanonical NF-κb signalling, but is impaired in primary sjögren’s syndrome

Abstract

BackgroundThe nuclear factor (NF)-κB family of transcription factors has a key role in the regulation of inflammation. We have previously demonstrated that activation of noncanonical NF-κB signalling in dendritic cells...