A17659 Long-term blood pressure-lowering effect of carotid artery stenting in patients with carotid artery stenosis

Abstract

Objectives: To evaluate the long-term blood pressure-lowering effects of carotid artery stenting (CAS) in patients with carotid artery stenosis and find out its predisposing factors on blood pressure (BP) lowering. Methods: 203 consecutive carotid artery stenosis patients underwent CAS from January 2016 to March 2017 were retrospectively analyzed in our institution. The office BP levels of all patients were monitored for 1 year. Thereafter, the preoperative levels of office BP were compared with office BP levels at the the first year intervals after the procedure. BP improvement was defined as an average reduction of systolic BP more than 10 mmHg. Results: Compared with preoperative level, the office systolic BP decreased from 141.6 ± 16.0 mmHg to 132.7 ± 12.2 mmHg (P < 0.01). Among them, 110 patients (54.2%) has BP improvement. The coronary artery bypass grafting (OR = 1.955, 95% CI, 1.116–3.425; p = 0.019), hemodynamic depression (OR = 4.064, 95%CI, 2.226–7.306; p < 0.001) and stent type (open-cell design) (OR = 2.362, 95%CI, 1.237 to 4.505; p = 0.009) were independent predisposing factors for BP-lowering effects of CAS by multivariate analysis. Conclusion: For patients with carotid artery stenosis, CAS might have a BP-lowering effect at the 1-year follow-up, especially in patients underwent coronary artery bypass grafting, hemodynamic depression or being implanted open-cell stents.