A17369 Application of Continuous Noninvasive Arterial Pressure Monitor in Patients with Cardiovascular Diseases plus Obstructive Sleep Apnea

Abstract

Objectives: The hemodynamics of patient with cardiovascular diseases (CVD) plus obstructive sleep apnea (OSA) is changeable and complicated. A new continuous noninvasive arterial pressure monitor (CNAP) has been validated in screening the hemodynamics. The aim of our study is to assess the performance of CNAP in patients with CVD plus OSA. Methods: The hemodynamics of patient with cardiovascular diseases (CVD) plus obstructive sleep apnea (OSA) is changeable and complicated. A new continuous noninvasive arterial pressure monitor (CNAP) has been validated in screening the hemodynamics. The aim of our study is to assess the performance of CNAP in patients with CVD plus OSA. Results: Compared with the values monitored before sleeping, patients had higher mean systolic blood pressure (125.60 ± 17.19mmHg vs. 118.96 ± 17.97mmHg, P < 0.05), lower mean heart rate (66.41 ± 9.19bpm vs. 69.61 ± 12.57bpm, P < 0.05) during sleep apnea events. 10 patients have used continuous positive airway pressure (CPAP) to treat OSA. Compared with the values monitored before treatment by CPAP, patients using CPAP had lower cardiac output (5.41 ± 1.12l/min vs. 5.74 ± 1.19l/min, P < 0.05), cardiac index (2.85 ± 0.40l/min/m^2 vs. 3.02 ± 0.4l/min/m^2, P < 0.05), pulse pressure variation (5.67 ± 1.20% vs. 6.48 ± 1.20%, P < 0.05) and stroke volume variation (7.47 ± 1.60% vs. 11.03 ± 2.78%, P < 0.05). Conclusion: CNAP could be clinically useful to assess hemodynamics of patient with CVD plus OSA. When sleep apnea events happened, patients’ mean systolic blood pressure became higher while mean heart rate became lower. When patients using CPAP, cardiac output, cardiac index, pulse pressure variation and stroke volume variation all became lower.