Abstract
Investigations concerning the blood AMPS pattern have been relatively few, probably owing to low AMPS concentration.An average AMPS uronic acid level of 206 μg% in normal human plasma has been reported(1), whereas an average concentration of 277 μg% was observed in normal serum (2). On paper chromatography of an AMPS fraction isolated from serum, 2 components, both of which were labile to testicular hyalu-ronidase, were observed(2). The chromato-graphic characteristics of one component resembled that of chondroitin sulfate (ChS). Schiller(3) presented conclusive evidence for ChS-A being the main AMPS of normal human plasma. Starting from several liters of human plasma she obtained 2 AMPS fractions. The nature of the electrophoretically slower fraction remained unresolved. Apparently it was heterogeneous and it probably contained hyaluronic acid (HA) as one component. In the serum of 2 patients with reticulum cell sarcoma and neuroblastoma, respectively, the presence of HA has been demonstrated (4).Zone el...
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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