Abstract

Using 2-[ 18 F]fluoro-2-deoxy-D-glucose (FDG) and positron emission tomography (PET), the kinetic models for FDG metabolism were established in tissue of myocardium, lung, stomach, spleen, pancreas, marrow, liver and kidneys. All submodels were connected by the circulation system, forming the whole body model. The model can be visualized on the base of Visible Human Project (VHP), to simulate the dynamic metabolic process of FDG in human body. The simulated FDG distribution images were in 2D and 3D formats, and presented higher resolution than original PET image. The result of this study can be used not only for education and related research, but also by PET operators to design their PET experiment program.

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