Abstract

Spatiotemporal parameters of gait serve as an important biomarker to monitor gait impairments as well as to develop rehabilitation systems. In this work, we developed a computationally-efficient algorithm (SDI-Step) that uses segmented double integration to calculate step length and step time from wearable inertial measurement units (IMUs) and assessed its ability to reliably and accurately measure spatiotemporal gait parameters. Two data sets that included simultaneous measurements from wearable sensors and from a laboratory-based system were used in the assessment. The first data set utilized IMU sensors and a GAITRite mat in our laboratory to monitor gait in fifteen participants: 9 young adults (YA1) (5 females, 4 males, age 23.6 ± 1 years), and 6 people with Parkinson’s disease (PD) (3 females, 3 males, age 72.3 ± 6.6 years). The second data set, which was accessed from a publicly-available repository, utilized IMU sensors and an optoelectronic system to monitor gait in five young adults (YA2) (2 females, 3 males, age 30.5 ± 3.5 years). In order to provide a complete representation of validity, we used multiple statistical analyses with overlapping metrics. Gait parameters such as step time and step length were calculated and the agreement between the two measurement systems for each gait parameter was assessed using Passing–Bablok (PB) regression analysis and calculation of the Intra-class Correlation Coefficient (ICC (2,1)) with 95% confidence intervals for a single measure, absolute-agreement, 2-way mixed-effects model. In addition, Bland–Altman (BA) plots were used to visually inspect the measurement agreement. The values of the PB regression slope were close to 1 and intercept close to 0 for both step time and step length measures. The results obtained using ICC (2,1) for step length showed a moderate to excellent agreement for YA (between 0.81 and 0.95) and excellent agreement for PD (between 0.93 and 0.98), while both YA and PD had an excellent agreement in step time ICCs (>0.9). Finally, examining the BA plots showed that the measurement difference was within the limits of agreement (LoA) with a 95% probability. Results from this preliminary study indicate that using the SDI-Step algorithm to process signals from wearable IMUs provides measurements that are in close agreement with widely-used laboratory-based systems and can be considered as a valid tool for measuring spatiotemporal gait parameters.

Highlights

  • Spatiotemporal gait parameters have been used to assess gait in healthy populations and those with pathologies [1,2,3,4,5,6,7]

  • For calculation of spatiotemporal gait parameters from data derived from wearable inertial measurement units (IMUs), several algorithms have been investigated, such as: wavelet transforms to identify gait events followed by the use of a double pendulum model to calculate stride length [6,7,16]; sensor fusion algorithms that use Magnetic

  • The mean of the errors for step length and step time measures obtained between the IMU system and the lab-based reference system were small

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Summary

Introduction

Spatiotemporal gait parameters have been used to assess gait in healthy populations and those with pathologies [1,2,3,4,5,6,7]. Angular Rate Gravity (MARG)-based adaptive-gain filters, Kalman filters, and extended Kalman filters [17,18] to estimate kinematic parameters such as gait phases, velocity, and position; and artificial neural network-based algorithms to classify the healthy and pathological population and estimate gait features such as minimum toe clearance and gait velocity [19,20,21]. These algorithms [6,7,17,18,19,20] have been used to calculate gait parameters such as velocity and stride length.

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