Abstract

Extracting sufficient volumes of sweat consistently in various scenarios is necessary for next-generation wearable sweat sensors. Here, we developed a sensor patch for Joule-heating sweating and comfortable biofluid monitoring. The Ti3C2Tx nanosheet provides silk fabrics with good electrical conductivity which can serve as an efficient low-voltage electrothermal platform. This biosensor can induce significant sweating in volunteers within just 5 minutes through mild heat stimulation, allowing real-time assessment of metabolic syndrome risks, including Na+, K+, pH, and uric acid levels. Unlike traditional sweat sensors that rely on iontophoresis or physical movement, our approach offered enhanced comfort and efficiency, particularly in sedentary scenarios. Such integration of Joule-heating sweating and sweat analysis endows its potential as a versatile and user-friendly tool in precision medicine and healthcare monitoring.

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